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Pierre Åman Selected Research

Myxoid Liposarcoma

4/2022Fusion protein-driven IGF-IR/PI3K/AKT signals deregulate Hippo pathway promoting oncogenic cooperation of YAP1 and FUS-DDIT3 in myxoid liposarcoma.
3/2022Different HSP90 Inhibitors Exert Divergent Effect on Myxoid Liposarcoma In Vitro and In Vivo.
1/2022FUS-DDIT3 Fusion Oncoprotein Expression Affects JAK-STAT Signaling in Myxoid Liposarcoma.
1/2019Requirement for YAP1 signaling in myxoid liposarcoma.
1/2019Phosphatidylinositol-3-kinase (PI3K)/Akt Signaling is Functionally Essential in Myxoid Liposarcoma.
1/2019JAK-STAT signalling controls cancer stem cell properties including chemotherapy resistance in myxoid liposarcoma.
1/2018Identification of inhibitors regulating cell proliferation and FUS-DDIT3 expression in myxoid liposarcoma using combined DNA, mRNA, and protein analyses.
10/2017FUS-DDIT3 Fusion Protein-Driven IGF-IR Signaling is a Therapeutic Target in Myxoid Liposarcoma.
1/2016Establishment and characterization of a new human myxoid liposarcoma cell line (DL-221) with the FUS-DDIT3 translocation.

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Pierre Åman Research Topics

Disease

9Myxoid Liposarcoma
04/2022 - 01/2016
7Neoplasms (Cancer)
03/2022 - 10/2017
5Sarcoma (Soft Tissue Sarcoma)
01/2022 - 04/2016
2Leukemia
01/2022 - 01/2019
1Fibrosarcoma
10/2017
1Hepatocellular Carcinoma (Hepatoma)
04/2016
1Cutaneous T-Cell Lymphoma (Lymphoma, T Cell, Cutaneous)
04/2016

Drug/Important Bio-Agent (IBA)

7Proteins (Proteins, Gene)FDA Link
04/2022 - 04/2016
5Transcription Factors (Transcription Factor)IBA
01/2022 - 01/2016
3Oncogene Proteins (Oncogene Protein)IBA
01/2022 - 01/2019
3Messenger RNA (mRNA)IBA
01/2020 - 10/2017
117- (dimethylaminoethylamino)- 17- demethoxygeldanamycinIBA
03/2022
15- (2,4- dihydroxy- 5- isopropylphenyl)- 4- (4- morpholin- 4- ylmethylphenyl)isoxazole- 3- carboxylic acid ethylamideIBA
03/2022
1ChromatinIBA
01/2022
1RNA Polymerase II (RNA Polymerase B)IBA
01/2022
1DNA (Deoxyribonucleic Acid)IBA
01/2018
1Biological ProductsIBA
10/2017
1Histone Deacetylase InhibitorsIBA
04/2016
1Histone Deacetylases (Histone Deacetylase)IBA
04/2016
1Biomarkers (Surrogate Marker)IBA
04/2016

Therapy/Procedure

5Therapeutics
03/2022 - 04/2016
2Drug Therapy (Chemotherapy)
01/2022 - 01/2019